Using megadose vitamin C to tackle septic shock

Research Pulse podcast: Episode 10

Could vitamin C save the lives of people in the intensive care unit?

In this episode, we discuss exciting new research using megadoses of a derivative of vitamin C, called sodium ascorbate, that could change the way sepsis is managed worldwide.

We’re speaking with Associate Professor Mark Plummer, Head of Research and Innovation in the Intensive Care Unit (ICU) at the Royal Adelaide Hospital, to learn about:

  • what sepsis is and its prevalence in ICU
  • how vitamin C could be used to treat sepsis
  • why sodium ascorbate may be more useful than other forms of vitamin C


About this research

Mark Plummer is Head of Research and Innovation in the Intensive Care Unit (ICU) at the Royal Adelaide Hospital and also a senior lecturer at the Adelaide Medical School, The University of Adelaide, and with the Department of Critical Care at the University of Melbourne.

Mark’s sepsis research is conducted with The Royal Melbourne Hospital and The Florey Institute of Neuroscience and Mental Health and is funded in part by grants from The Hospital Research Foundation Group, as well as the Medical Research Future Fund.



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